Research & Evidence
Comprehensive scientific research supporting Aloe vera barbadensis and acemannan for skin health, gut comfort, and metabolic support
Research Database
Search and filter through our comprehensive collection of scientific studies
71
Clinical Outcomes
10
Systematic Reviews
67%
Significant Results
2021
Latest Review
Research Evidence by Health Area
Comprehensive research findings from systematic reviews and clinical trials
Blood Sugar Control
Evidence Level: Strong (Human/Animal trials)
Multiple studies show aloe vera juice can lower fasting blood glucose in type 2 diabetic and prediabetic individuals.
Key Research Findings:
- • Significant reduction in fasting blood glucose
- • Improved glycemic control in type 2 diabetes
- • Beneficial effects in prediabetic individuals
Cholesterol & Heart Health
Evidence Level: Strong (Human/Animal trials)
Research shows aloe vera can reduce LDL cholesterol, total cholesterol, triglycerides, and may increase HDL cholesterol.
Key Research Findings:
- • Reduces LDL (bad cholesterol)
- • Lowers total cholesterol levels
- • Decreases triglyceride levels
- • May increase HDL (good cholesterol)
Wound Healing
Evidence Level: Strong (Topical/Oral)
Accelerates cell proliferation, migration, and reduces recovery time for burns and minor injuries.
Key Research Findings:
- • Accelerates cell proliferation and migration
- • Reduces recovery time for burns
- • Effective for minor injuries
- • Stimulates fibroblast proliferation
- • Enhances collagen production
Digestive Health
Evidence Level: Strong
Acts as mild laxative, supports beneficial gut bacteria, may reduce gastritis and acid reflux.
Key Research Findings:
- • Acts as mild laxative (due to aloin)
- • Aids constipation relief
- • Supports beneficial gut bacteria
- • May reduce gastritis and acid reflux
- • Improves overall gastrointestinal health
Antioxidants & Skin
Evidence Level: Moderate
Polyphenols, vitamins A, C, E protect skin from oxidative stress and may slow visible aging signs.
Key Research Findings:
- • Contains polyphenols and vitamins A, C, E
- • Protects skin from oxidative stress
- • May slow visible signs of aging
- • Antioxidant activity supports skin health
Immune Support
Evidence Level: Limited
Polysaccharides show immunomodulatory effects; some in vitro studies suggest antiviral/antibacterial activity.
Key Research Findings:
- • Polysaccharides show immunomodulatory effects
- • Some in vitro studies suggest antiviral activity
- • Some in vitro studies suggest antibacterial activity
- • More human research needed for confirmation
Specific Research Results
Actual findings and data from clinical studies and systematic reviews
Blood Sugar Control Results
Meta-Analysis Results (2016)
Systematic review of 8 randomized controlled trials
- • Fasting Blood Glucose: Significant reduction
- • HbA1c: Improved glycemic control
- • Study Population: Type 2 diabetic patients
Clinical Trial Findings
Multiple human trials show consistent results
- • Duration: 4-12 week studies
- • Dosage: 300-1000mg daily
- • Outcome: Improved glucose metabolism
Cholesterol Reduction Results
Lipid Profile Improvements
Clinical studies show significant lipid improvements
- • LDL Cholesterol: 15-20% reduction
- • Total Cholesterol: 10-15% reduction
- • Triglycerides: 20-25% reduction
- • HDL Cholesterol: Potential increase
Study Parameters
Consistent across multiple trials
- • Study Duration: 8-12 weeks
- • Population: Hyperlipidemic patients
- • Mechanism: Enhanced lipid metabolism
Wound Healing Results
Clinical Trial Data (2003)
PMC Clinical Trials on Wound Prevention & Treatment
- • Healing Time: 67% faster than control
- • Cell Proliferation: Significantly enhanced
- • Collagen Production: Increased synthesis
Mechanism of Action
Scientific understanding of healing process
- • Fibroblast Stimulation: Enhanced proliferation
- • Anti-inflammatory: Reduces swelling
- • Antimicrobial: Prevents infection
Digestive Health Results
Laxative Effects
Clinical studies on constipation relief
- • Onset: 6-12 hours after consumption
- • Mechanism: Aloin stimulates peristalsis
- • Safety: Mild, well-tolerated effect
Gut Microbiome Support
Research on beneficial bacteria
- • Prebiotic Effect: Feeds beneficial bacteria
- • Gastritis Relief: Anti-inflammatory properties
- • Acid Reflux: Potential symptom reduction
Science-Backed Ingredients
Our approach is grounded in peer-reviewed research and ingredient-level literature. Explore the scientific foundation behind acemannan and aloe vera barbadensis.
General Benefits & Safety
Comprehensive overviews of aloe vera juice benefits, side effects, and safety considerations from leading health organizations.
Key Constituents & Pharmacology
Peer-reviewed research on acemannan, aloin, and aloe-emodin mechanisms and therapeutic potential.
Metabolic & Gut Health
Research on glucose regulation, lipid management, and digestive comfort from clinical trials and reviews.
Skin & Immune Health
Literature on topical applications, immune support, and wound healing properties of aloe constituents.
Evidence Level Summary
| Health Benefit | Evidence Level | Research Support |
|---|---|---|
| Lowers blood sugar | Strong | Human/Animal trials |
| Reduces LDL cholesterol | Strong | Human/Animal trials |
| Improves wound healing | Strong | Topical/Oral studies |
| Helps constipation | Strong | Clinical trials |
| Antioxidant, anti-aging | Moderate | In vitro studies |
| Immunity boost, antimicrobial | Limited | In vitro studies |
Disclaimer: These sources are provided for ingredient education only. NASIA is not a medical treatment and does not cure, mitigate, or treat diseases. Consult healthcare professionals for medical advice.
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